Plenary Lectures
Lecture Hall
28.2.2025
08:30 – 12:15h
Symposium 1
Chair: TBD
HS-AFM single-molecule observation identifies a unique mechanism of ABCA1-mediated nascent HDL generation
Kodan, Atsushi (Japan)
09:30h - 10:15h
Plenary Lectures
Lecture Hall
28.2.2025
08:30 – 12:15h
Symposium 1
Chair: TBD
Mechanistic Insights into Polysaccharide Translocating ABC Transporters
Zimmer, Jochen (United States of America)
10:15h - 11:00h
Plenary Lectures
Lecture Hall
28.2.2025
08:30 – 12:15h
Symposium 1
Chair: TBD
Introduction
Chair: TBD
08:30h - 08:45h
Plenary Lectures
Lecture Hall
28.2.2025
08:30 – 12:15h
Symposium 1
Chair: TBD
Bacterial resilience: multi-level hierarchical regulation of the osmolyte importer OpuA
Paulino, Cristina (Germany)
08:45h - 09:30h
Plenary Lectures
Lecture Hall
3.3.2025
08:30 – 12:15h
Symposium 4
Chair: Arne Moeller
Structure and mechanism of Plant hormone ABC transporters
ZHANG, PENG (China)
08:30h - 09:15h
Plenary Lectures
Lecture Hall
3.3.2025
08:30 – 12:15h
Symposium 4
Chair: Arne Moeller
Structural analyses of a peptidase-ABC transporter that activates specialized bacterial metabolites
Gaudet, Rachelle (United States of America)
09:15h - 10:00h
Plenary Lectures
Lecture Hall
3.3.2025
08:30 – 12:15h
Symposium 4
Chair: Arne Moeller
An ABC transporter required for light gradient formation in a photosensitive plant tissue
Fankhauser, Christian (Switzerland)
10:45h - 11:30h
Plenary Lectures
Lecture Hall
2.3.2025
08:30 – 12:15h
Symposium 3
Chair: TBD
Mycobacterial ABC transporter IrtAB imports iron-loaded siderophores via a non-canonical transport route
Seeger, Markus (Switzerland)
08:30h - 09:15h
Plenary Lectures
Lecture Hall
1.3.2025
08:30 – 12:15h
Symposium 2
Plenary Lectures
Lecture Hall
1.3.2025
08:30 – 12:15h
Symposium 2
Studying the molecular mechanisms of ABC transporters under physiologically relevant conditions
Zoghbi, Maria (United States of America)
10:15h - 11:00h
Plenary Lectures
Lecture Hall
1.3.2025
08:30 – 12:15h
Symposium 2
Impact of lipids and genetic modulations on the transport cycle and drug interaction of ABC transporters
Tajkhorshid, Emad (United States of America)
09:30h - 10:15h
Keynote Plenary Lecture
Lecture Hall
1.3.2025
20:30 – 21:30h
Keynote Plenary Lecture
Chair: Gergely Szakacs
Lonely channel among transporter siblings: structure and mechanism of the CFTR anion channel
Csanády, László (Hungary)
20:30h - 21:30h
More than Anagrams: MsbA and SbmA, a Link Between Primary and Secondary Transporters
Slotboom, Dirk (Netherlands)
17:00h - 17:15h
When Less is MORE: Functional Proteomics of ABC Importers reveal Essential Roles of Cellular Abundances and Counterintuitive Stoichiometries
Lewinson, Oded (Israel)
17:15h - 17:30h
Blood-Brain Barrier Dysfunction in Alzheimer’s Disease: An Environmental Health Perspective
Hartz, Anika (United States of America)
17:30h - 17:45h
Regulation of Peroxisomal CoA and Fatty Acid Metabolism in S. cerevisiae by ABCD Transporters and two Porins
van Roermund, Carlo W.T. (Netherlands)
17:45h - 18:00h
A tractable culture system of human liver for the study of your favourite (ABC) transporters
Linton, Kenneth (United Kingdom)
18:00h - 18:15h
The type III secreted effector EspZ of enteropathogenic E. coli protects against lytic host cell death by targeting ABCB6
Aroeti, Benjamin (Israel)
18:15h - 18:30h
Role of CFTR in Kidney
Cebotaru, Liudmila (United States of America)
18:30h - 18:45h
Elucidation of mechanisms underlying female infertility in Abcg5/g8 knockout mice
Yamanashi, Yoshihide (Japan)
18:45h - 19:00h
Plenary Lectures
Lecture Hall
2.3.2025
08:30 – 12:15h
Symposium 3
Chair: TBD
CFTR – the most strange ABC pore
Nikhil Bharti (Germany)
10:45h - 11:30h
Plenary Lectures
Lecture Hall
1.3.2025
08:30 – 12:15h
Symposium 2
Structural basis of specific and nonspecific ABC transporters
Liao, Maofu (China)
08:45h - 09:30h
Time-resolved structural transitions of the multidrug transporter BmrA using rapid kinetics and time-resolved cryoEM
Moissonnier, Loïck (France)
17:45h - 18:00h
Structural and mechanistic insights into lipid-linked galactan transport by the mycobacterial ABC transporter Wzm-Wzt
Garaeva, Alisa (Switzerland)
18:00h - 18:15h
Structural Insights into Human Peroxisomal ABC Transporters ABCD1 and ABCD3: Mechanisms of Fatty Acid Transport and Disease Pathology
Hou, Wen-Tao (China)
18:15h - 18:30h
Challenge the Undruggable – An Optimized Chemical Probe to Target Conserved Binding Domains of Membrane Transporters
Stefan, Sven Marcel (Germany)
18:30h - 18:45h
Investigating the Enigmatic Phenomenon of Drug Efflux by Deep Mutational Scanning
Thavarasah, Sujani (Switzerland)
18:45h - 19:00h
Computational Microscopy of Heme Flipping During Passive Transport and through a Bacterial ABC Transporter
ebrahimi, mina (Belgium)
19:00h - 19:15h
Structural Aspects of Unspecific Ligand Recognition in Multidrug Transporters – Why are Weak Binders Strong Inhibitors?
Gyimesi, Gergely (Germany)
19:15h - 19:30h
Plenary Lectures
Lecture Hall
28.2.2025
08:30 – 12:15h
Symposium 1
Chair: TBD
The role of ABCB10 controlling mitochondrial redox in health and disease.
Liesa Roig, Marc (Spain)
11:00h - 11:45h
Plenary Lectures
Lecture Hall
1.3.2025
08:30 – 12:15h
Symposium 2
Mycobacterial galactan exporter Wzm-Wzt – from discovery to structural insights
Mikušová, Katarína (Slovakia)
11:00h - 11:45h
Opening Plenary Lecture
Lecture Hall
27.2.2025
19:30 – 20:30h
Opening Plenary Lecture
Chair: Piet Borst (NL)
TBD
Sharon TERRY
19:30h - 20:30h
ABCG1 localizes to the lipid rafts by palmitoylation and regulates their dynamics
Yamanaka, Yuto (Japan)
17:00h - 17:15h
Cryo-EM Analyses of the Conformational Spectrum of a Nucleotide-Bound ABC Transporter in Various Membrane Mimics
Baier, Anika (Germany)
17:15h - 17:30h
Peptide transport across membranes visualized at single-molecule level
Nocker, Christoph (Germany)
17:30h - 17:45h
Single-molecule observations of B 12 transport elucidate BtuCD-F mechanism
Loughlin, Blaine (United States of America)
17:45h - 18:00h
Hierarchical protein unfolding at the site of a functional conformational change in human CFTR is the Achilles' Heel controlling biogenesis efficiency and corrector-drug mechanism.
Paige, Andrew (United States of America)
18:00h - 18:15h
Structural characterization of two interacting intrinsically disordered regions in the SUR2 regulatory subunit of ATP-sensitive potassium channels
Tymczak, Agatha (Canada)
18:15h - 18:30h
The conformational landscape of LptC during lipopolysaccharide transport
Klausnitzer, Aaron (Germany)
18:30h - 18:45h
Measurement of the activity of multidrug resistance-associated proteins in human tissues with long axial field-of-view PET imaging
Jackwerth, Matthias (Austria)
18:45h - 19:00h
Plenary Lectures
Lecture Hall
2.3.2025
08:30 – 12:15h
Symposium 3
Chair: TBD
H. Mchaourab
09:15h - 10:00h
Plenary Lectures
Lecture Hall
2.3.2025
08:30 – 12:15h
Symposium 3
Chair: TBD
T. Tomasiak
10:00h - 10:45h
Plenary Lectures
Lecture Hall
3.3.2025
08:30 – 12:15h
Symposium 4
Chair: Arne Moeller
Ute Hellmich
10:00h - 10:45h
TBA
Karl Kuchler
17:30h - 18:30h
Plenary Lectures
Lecture Hall
1.3.2025
17:00 – 17:45h
Symposium 5
The Clinical Relevance of ABC Transporters in Cancer Multidrug Resistance: Phoenix or Icarus?
Michael M. Gottesman
17:00h - 17:45h